Frank Wappler Selected Research

Fidaxomicin

2/2017

Successful treatment of severe Clostridium difficile infection by administration of crushed fidaxomicin via a nasogastric tube in a critically ill patient.

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Frank Wappler Research Topics

Disease

16	Malignant Hyperthermia 06/2015 - 08/2002
9	Wounds and Injuries (Trauma) 01/2020 - 01/2006
8	Critical Illness (Critically Ill) 06/2019 - 04/2009
8	Contracture 01/2011 - 08/2002
3	Intraoperative Complications 10/2022 - 01/2018
3	Infections 01/2019 - 04/2009
3	Delirium 10/2018 - 02/2010
3	Hyperthermia 01/2013 - 11/2003
2	Thoracic Injuries (Chest Injury) 03/2020 - 01/2020
2	Pain (Aches) 03/2020 - 09/2016
2	Burns 03/2020 - 06/2019
2	Neuralgia (Stump Neuralgia) 03/2020 - 09/2016
2	Sepsis (Septicemia) 06/2019 - 02/2008
2	Propofol Infusion Syndrome 10/2017 - 07/2006
2	Pneumonia (Pneumonitis) 04/2009 - 02/2009
2	Tachycardia (Tachyarrhythmias) 01/2008 - 03/2007
2	Hypertensive Crisis 01/2008 - 03/2007
1	Tracheal Stenosis 10/2022
1	COVID-19 08/2021
1	Emphysema 04/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2021
1	Subcutaneous Emphysema 04/2021
1	Foreign Bodies (Foreign Body) 01/2021
1	Pneumothorax 01/2020
1	Respiratory Sounds (Crackle) 12/2019
1	Cicatrix (Scar) 12/2019
1	Pathologic Constriction (Stenosis) 12/2019
1	Inflammation (Inflammations) 01/2019
1	Intra-Abdominal Hypertension 01/2019
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2019
1	Obesity 01/2019
1	Neoplasms (Cancer) 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 01/2018
1	Healthcare-Associated Pneumonia 11/2017
1	Muscular Diseases (Myopathy) 10/2017
1	Mitochondrial Myopathies (Mitochondrial Myopathy) 10/2017
1	Septic Shock (Toxic Shock Syndrome) 02/2017
1	Acute Kidney Injury (Acute Renal Failure) 02/2017
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2017
1	Clostridium Infections 02/2017
1	Lung Neoplasms (Lung Cancer) 09/2016
1	Obstructive Sleep Apnea 01/2016
1	Multiple Trauma (Multiple Injuries) 07/2014
1	Leukemia 06/2013
1	Hypercapnia 01/2013
1	Air Embolism (Gas Embolism) 01/2013
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2013
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2012
1	Cerebral Infarction 07/2011
1	Body Weight (Weight, Body) 04/2011
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 02/2011

Drug/Important Bio-Agent (IBA)

4	Dantrolene (Dantrium)FDA LinkGeneric 01/2013 - 11/2003
4	Halothane (Fluothane)FDA Link 04/2011 - 08/2002
3	Anesthetics (Anesthetic Agents)IBA 10/2022 - 06/2015
3	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 01/2013 - 11/2003
3	Caffeine (No Doz)FDA LinkGeneric 04/2004 - 08/2002
2	ProcalcitoninIBA 06/2019 - 02/2008
2	Anti-Bacterial Agents (Antibiotics)IBA 06/2019 - 02/2009
2	SuspensionsIBA 01/2013 - 04/2011
2	CalciumIBA 01/2012 - 10/2002
2	CatecholaminesIBA 01/2008 - 03/2007
2	RyanodineIBA 08/2004 - 08/2002
2	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 10/2002 - 08/2002
1	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 03/2020
1	Analgesics (Analgesic Drugs)IBA 03/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2019
1	Propofol (Diprivan)FDA LinkGeneric 10/2017
1	Succinylcholine (Suxamethonium Chloride)FDA LinkGeneric 10/2017
1	FidaxomicinIBA 02/2017
1	Lipoproteins (Lipoprotein)IBA 02/2017
1	Metronidazole (Metric)FDA LinkGeneric 02/2017
1	Glucose (Dextrose)FDA LinkGeneric 02/2017
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2017
1	Vancomycin FDA LinkGeneric 02/2017
1	IonsIBA 01/2012
1	Therapeutic UsesIBA 04/2011
1	SolutionsIBA 04/2011
1	Lactic Acid (Lactate)FDA LinkGeneric 04/2011

Therapy/Procedure

12	Therapeutics 01/2020 - 11/2003
5	Critical Care (Surgical Intensive Care) 08/2021 - 02/2010
4	Artificial Respiration (Mechanical Ventilation) 03/2020 - 01/2019
4	Anesthesia 01/2016 - 06/2010
3	Thoracotomy 04/2021 - 09/2016
3	Length of Stay 03/2020 - 10/2018
2	Chest Tubes (Chest Tube) 04/2021 - 01/2020
2	Operative Surgical Procedures 01/2021 - 06/2019
2	Drug Therapy (Chemotherapy) 01/2019 - 09/2012
2	Analgesia 01/2015 - 02/2010
2	General Anesthesia 11/2008 - 04/2003
1	Airway Management 10/2022
1	Laryngoscopes 01/2021
1	First Aid (Aids, First) 03/2020
1	Injections 12/2019
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2018
1	Catheters 11/2017
1	Denervation 09/2016
1	Central Venous Catheters 01/2013
1	Tracheostomy 12/2012
1	Decompressive Craniectomy 07/2011
1	Punctures 02/2011